foxk2 expression data Search Results


foxk2 expression data  (Human Protein Atlas)
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Human Protein Atlas foxk2 expression data
Association between <t> FOXK2 expression </t> and gastric cancer clinicopathological features.
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Association between FOXK2 expression and gastric cancer clinicopathological features.

Journal: Molecular Medicine Reports

Article Title: Downregulation of FOXK2 is associated with poor prognosis in patients with gastric cancer

doi: 10.3892/mmr.2018.9466

Figure Lengend Snippet: Association between FOXK2 expression and gastric cancer clinicopathological features.

Article Snippet: FOXK2 expression data in gastric cancer were collated from the Human Protein Atlas ( ).

Techniques: Expressing

Univariate and multivariate analyses of prognostic parameters in patients with gastric cancer in terms of overall survival.

Journal: Molecular Medicine Reports

Article Title: Downregulation of FOXK2 is associated with poor prognosis in patients with gastric cancer

doi: 10.3892/mmr.2018.9466

Figure Lengend Snippet: Univariate and multivariate analyses of prognostic parameters in patients with gastric cancer in terms of overall survival.

Article Snippet: FOXK2 expression data in gastric cancer were collated from the Human Protein Atlas ( ).

Techniques: Expressing

Expression of FOXK2 in gastric cancer tissues. (A) Kaplan-Meier analysis of OS and PFS based on FOXK2 expression in patients with gastric cancer (log-rank test, P<0.01). (B) Kaplan-Meier analysis for survival was performed with data obtained from The Human Protein Atlas (log-rank test, P=0.0224). (C) Immunohistochemical staining of FOXK2 in various gastric cancer grades (magnification, ×200). The results were analyzed with one-way analysis of variance followed by Student-Newman-Keuls method; *P<0.05. (D) Compared with para-tumor tissue samples, relative FOXK2 mRNA expression was significantly lower in tumor tissue samples. FOXK2, forkhead box K2; OS, overall survival; PFS, progression free survival.

Journal: Molecular Medicine Reports

Article Title: Downregulation of FOXK2 is associated with poor prognosis in patients with gastric cancer

doi: 10.3892/mmr.2018.9466

Figure Lengend Snippet: Expression of FOXK2 in gastric cancer tissues. (A) Kaplan-Meier analysis of OS and PFS based on FOXK2 expression in patients with gastric cancer (log-rank test, P<0.01). (B) Kaplan-Meier analysis for survival was performed with data obtained from The Human Protein Atlas (log-rank test, P=0.0224). (C) Immunohistochemical staining of FOXK2 in various gastric cancer grades (magnification, ×200). The results were analyzed with one-way analysis of variance followed by Student-Newman-Keuls method; *P<0.05. (D) Compared with para-tumor tissue samples, relative FOXK2 mRNA expression was significantly lower in tumor tissue samples. FOXK2, forkhead box K2; OS, overall survival; PFS, progression free survival.

Article Snippet: FOXK2 expression data in gastric cancer were collated from the Human Protein Atlas ( ).

Techniques: Expressing, Immunohistochemical staining, Staining

FOXK2 expression affects c-caspase-3 expression and BGC-823 cell apoptosis. (A) si-FOXK2 transfection effectively reduced FOXK2 mRNA expression in BGC-823 cells, as well as (B) FOXK2 and c-caspase-3 protein expression. (C) FOXK2 overexpression plasmid transfection successfully increased FOXK2 mRNA. (D) FOXK2 and c-caspase-3 protein expression also increased. (E) si-FOXK2 decreased BGC-823 cell apoptosis, whereas (F) FOXK2 overexpression increased BGC-823 cell apoptosis. *P<0.05, **P<0.01 vs. the corresponding control group. c-, cleaved; FITC, fluorescein isothiocyanate; FOXK2, forkhead box K2; NC, negative control; PI, propidium iodide; si-, small interfering RNA.

Journal: Molecular Medicine Reports

Article Title: Downregulation of FOXK2 is associated with poor prognosis in patients with gastric cancer

doi: 10.3892/mmr.2018.9466

Figure Lengend Snippet: FOXK2 expression affects c-caspase-3 expression and BGC-823 cell apoptosis. (A) si-FOXK2 transfection effectively reduced FOXK2 mRNA expression in BGC-823 cells, as well as (B) FOXK2 and c-caspase-3 protein expression. (C) FOXK2 overexpression plasmid transfection successfully increased FOXK2 mRNA. (D) FOXK2 and c-caspase-3 protein expression also increased. (E) si-FOXK2 decreased BGC-823 cell apoptosis, whereas (F) FOXK2 overexpression increased BGC-823 cell apoptosis. *P<0.05, **P<0.01 vs. the corresponding control group. c-, cleaved; FITC, fluorescein isothiocyanate; FOXK2, forkhead box K2; NC, negative control; PI, propidium iodide; si-, small interfering RNA.

Article Snippet: FOXK2 expression data in gastric cancer were collated from the Human Protein Atlas ( ).

Techniques: Expressing, Transfection, Over Expression, Plasmid Preparation, Control, Negative Control, Small Interfering RNA

FOXK2 regulates gastric cancer cell invasion. Western blot analysis demonstrated alterations in N-cadherin and E-cadherin expression following (A) si-FOXK2 or (B) FOXK2 plasmid transfection. Transwell assays were performed to assess the invasion of cells transfected with (C) si-FOXK2 or (D) FOXK2 plasmid. Magnification, ×200. *P<0.05, **P<0.01 vs. the corresponding control group. FOXK2, forkhead box K2; NC, negative control; si-, small interfering RNA.

Journal: Molecular Medicine Reports

Article Title: Downregulation of FOXK2 is associated with poor prognosis in patients with gastric cancer

doi: 10.3892/mmr.2018.9466

Figure Lengend Snippet: FOXK2 regulates gastric cancer cell invasion. Western blot analysis demonstrated alterations in N-cadherin and E-cadherin expression following (A) si-FOXK2 or (B) FOXK2 plasmid transfection. Transwell assays were performed to assess the invasion of cells transfected with (C) si-FOXK2 or (D) FOXK2 plasmid. Magnification, ×200. *P<0.05, **P<0.01 vs. the corresponding control group. FOXK2, forkhead box K2; NC, negative control; si-, small interfering RNA.

Article Snippet: FOXK2 expression data in gastric cancer were collated from the Human Protein Atlas ( ).

Techniques: Western Blot, Expressing, Plasmid Preparation, Transfection, Control, Negative Control, Small Interfering RNA

FOXK2 regulates gastric cancer cell proliferation. (A) Growth curve of cultured BGC-823 cells and the colony formation assay demonstrated that si-FOXK2 transfection induced cell proliferation, whereas (B) FOXK2 overexpression inhibited cell proliferation. (C) Wound-healing assays demonstrated that si-FOXK2 transfection increased cell migration, whereas (D) FOXK2 plasmid transfection inhibited cell migration. Magnification, ×100. *P<0.05 vs. the corresponding control group. FOXK2, forkhead box K2; NC, negative control; si-, small interfering RNA.

Journal: Molecular Medicine Reports

Article Title: Downregulation of FOXK2 is associated with poor prognosis in patients with gastric cancer

doi: 10.3892/mmr.2018.9466

Figure Lengend Snippet: FOXK2 regulates gastric cancer cell proliferation. (A) Growth curve of cultured BGC-823 cells and the colony formation assay demonstrated that si-FOXK2 transfection induced cell proliferation, whereas (B) FOXK2 overexpression inhibited cell proliferation. (C) Wound-healing assays demonstrated that si-FOXK2 transfection increased cell migration, whereas (D) FOXK2 plasmid transfection inhibited cell migration. Magnification, ×100. *P<0.05 vs. the corresponding control group. FOXK2, forkhead box K2; NC, negative control; si-, small interfering RNA.

Article Snippet: FOXK2 expression data in gastric cancer were collated from the Human Protein Atlas ( ).

Techniques: Cell Culture, Colony Assay, Transfection, Over Expression, Migration, Plasmid Preparation, Control, Negative Control, Small Interfering RNA